Things to Consider
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If you have a full sibling match or a 10/10 unrelated match a Full Match Bone Marrow Transplant may be your best option.
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If you do not have a full sibling match or any 10/10 donors available haploid identical transplant or gene therapy should be considered.
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Gene therapy has a high success rate, however you must be 12 years of age or older and must be willing for the process to take 8 to 12 months.
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Gene therapy for sickle cell has been around since 2015 while its counter parts have been around longer.
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Curative treatments are typically performed on children who are 16 and younger who have complications from their sickle cell disease who still have healthy organ function. This is not to say that adults living with sickle cell cannot get a transplant or gene therapy, this is dependent on their health and their medical provider's discretion.
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Please consult with multiple medical professionals before making any decisions.
Sources of Information
https://www.hopkinsmedicine.org/news/newsroom/news-releases/2023/12/a-cure-for-sickle-cell-disease
https://www.chop.edu/news/researchers-publish-final-results-key-clinical-trial-gene-therapy-sickle-cell-disease
https://www.fda.gov/news-events/press-announcements/fda-approves-first-gene-therapies-treat-patients-sickle-cell-disease#:~:text=The%20safety%20and%20effectiveness%20of%20Lyfgenia%20is%20based%20on%20the,CR%20during%20this%20time%20period.
https://www.yalemedicine.org/news/gene-therapies-sickle-cell-disease
https://crisprtx.com/focus-areas/hemoglobinopathies
https://www.healthline.com/health/is-there-a-cure-for-sickle-cell-anemia#issues
https://www.nejm.org/doi/full/10.1056/NEJM199608083350601
https://dhhr.wv.gov/bph/programs/Documents/BMT-for-sickle-cell-disease.pdf
https://www.stjude.org/care-treatment/treatment/blood-disorders/sickle-cell/sickle-cell-disease.html#:~:text=Jude%20patient%20was%20the%20first,children%20with%20sickle%20cell%20disease.